Table 4.

Impact of kidney transplantation on the hazard rate of death caused by a cardiovascular event (n = 175; 32 deaths: 19 pretransplant and 13 post-transplant)

Predictor Variables in the Modela	Cox Model (Coefficient ± SE)	Wald Test (P)	Adjusted Relative Risk [95% Confidence Interval]
Overall post-Tx effect	−1.632 ± 0.443	0.0002	0.20 [0.08 to 0.47]
Listed for kidney/pancreas Txb	2.110 ± 0.495	0.00002	8.25 [3.13 to 21.78]
Age at listing (continuous)	0.063 ± 0.018	0.0003	1.07 [1.03 to 1.10]
White race	0.727 ± 0.391	0.06	2.07 [0.96 to 4.45]

Tx, transplant.

^aOne overall effect of transplantation over time, adjusting for three significant baseline covariates. Of note, by allowing three distinct time period effects during 0 to 6, 7 to 84, and >84 months after transplant, the estimated hazard ratio was <1 during each period with no significant differences (P = 0.45). Among the 13 post-transplant cardiovascular deaths, there were 1, 6, and 6 deaths that occurred during 0 to 12, 12 to 84, and >84 months after transplantation, respectively.

^bAll patients listed for a kidney-pancreas transplant were type 1 diabetics.