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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Hepatology. 2011 May;53(5):1719–1729. doi: 10.1002/hep.24255

Figure 2. Co-culture of hAECs with Mouse hepatocytes improves hepatic differentiation of hAECs.

Figure 2

(A) Gene expression of hAECs after co-culture with mouse hepatocytes (mHeps) at day 16. mRNA levels expressed as arbitrary numbers normalized to Cyclophilin-A and relative to mRNA levels at day 1. (B) Testosterone metabolism of hAECs after co-culture with mHeps at day 20, after 3-days induction with Rifampicin and Phenobarbital. Results measured by HPLC and expressed as 6β-hydroxytestosterone metabolite formation, relative to mHep control sample. *P < 0.05; **P < 0.005; #P < 0.001.