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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Immunol. 2010 May 3;184(11):6479–6491. doi: 10.4049/jimmunol.0903867

Figure 9.

Figure 9

A schematic representation of SP-A dynamics among the amniotic fluid, placental amnion (amnion overlying the placental disc), and the reflected amnion (amnion of the extraplacental chorioamniotic membranes). There is a redistribution of SP-A in the amniotic fluid and the amnion with labor. HMW SP-A oligomers are more abundant in the placental amnion compared to the reflected amnion before labor. With labor at term, increased binding of HMW SP-A oligomers to the reflected amnion results in a decrease of amniotic fluid SP-A. Decreased amniotic fluid SP-A concentration during labor (23) is consistent with this model.