Table.
Sensitivity and positive predictive values of family history as a predictor of thrombophilic defects in 324 women with no personal history of venous thromboembolism
| Family history | All defects
|
Factor V Leiden
|
G20120A
|
|||||
|---|---|---|---|---|---|---|---|---|
| No (%) | 95% CI | No (%) | 95% CI | No (%) | 95% CI | |||
| First and second degree | ||||||||
| Sensitivity | 3/19 (16) | 0.0 to 32 | 2/10 (20) | 0.0 to 45 | 0/8 | — | ||
| Postive predictive value | 3/34 (9) | 0.0 to 18.3 | 2/34 (6) | 0.0 to 14 | 0/34 | — | ||
| First degree only | ||||||||
| Sensitivity | 2/19 (11) | 0 to 24.7 | 1/10 (10) | 0 to 28 | 0/8 | — | ||
| Postive predictive value | 2/26 (8) | 0 to 18 | 1/26 (4) | 0 to 11.2 | 0/26 | — | ||