Table 1.

Body and heart masses, blood pressure, and histological data

Parameter	STC	STC + S	FAT	FAT + S	FRU	FRU + S	SUC	SUC + S
Baseline body mass (g)	381 ± 5	378 ± 9	370 ± 10	375 ± 8	360 ± 9	371 ± 18	384 ± 9	381 ± 4
Final body mass (g)	473 ± 8	427 ± 24*	457 ± 18	440 ± 12	420 ± 9	373 ± 23*,†	468 ± 13	409 ± 15*
Body fat (%)	20.4 ± 2.1	19.9 ± 2.9	27.0 ± 1.6||	20.0 ± 1.5*	27.9 ± 2.1||	17.1 ± 2.3*	28.8 ± 1.2||	21.4 ± 2.3*
Arterial Systolic Blood Pressure (mmHg)
Baseline	127 ± 0.6	127 ± 1.2	128 ± 0.5	126 ± 0.9	127 ± 0.9	127 ± 0.7	127 ± 0.4	126 ± 0.6
6 weeks	126 ± 0.7	222 ± 0.9*	174 ± 1.1†	222 ± 0.9*	189 ± 0.9†	225 ± 1.1*	205 ± 1.3†	225 ± 1.8*
Body fat (%)	20.4 ± 2.1	19.9 ± 2.9	27.0 ± 1.6||	20.0 ± 1.5*	27.9 ± 2.1||	17.1 ± 2.3*	28.8 ± 1.2||	21.4 ± 2.3*
LV mass (g)	1.01 ± 0.02	1.26 ± 0.06*	0.91 ± 0.03	1.24 ± 0.04*	0.82 ± 0.02	1.17 ± 0.06*	1.07 ± 0.02‡	1.32 ± 0.05*
LV mass/body mass (mg/g)	2.14 ± 0.04	3.00 ± 0.19*	2.00 ± 0.04	2.82 ± 0.06*	1.96 ± 0.04	3.17 ± 0.09*,†	2.29 ± 0.09§	3.23 ± 0.16*,†
LV mass/tibial length (mg/cm)	251 ± 7	307 ± 13*	225 ± 9	304 ± 10*	200 ± 5	290 ± 12*	261 ± 7‡	320 ± 16*
RV mass/tibial length (mg/cm)	66 ± 3	70 ± 5	65 ± 5	76 ± 5	61 ± 2	67 ± 3	67 ± 4	71 ± 7
Myocyte cross-sectional area (μm2)	467 ± 15	546 ± 26	472 ± 37	533 ± 33	457 ± 25	539 ± 31	467 ± 47	551 ± 41
Interstitial fibrosis (%)	10.6 ± 0.7	ND	ND	ND	10.6 ± 0.7	10.5 ± 0.8	10.4 ± 0.8	9.7 ± 0.6
LV protein fractional synthesis rate (% newly made protein/hr)	1.05 ± 0.09	1.09 ± 0.10	0.82 ± 0.06	1.11 ± 0.08*	1.03 ± 0.08	1.02 ± 0.08	0.96 ± 0.11	1.14 ± 0.08

Values are means ± SEM. FAT, fat; FRU, fructose; LV, left ventricular; RV, right ventricular; S, salt; STC, starch; SUC, sucrose. ND, analysis was not done for these groups.

^*P <0.05 vs. same diet with low salt.

^†P <0.05 vs. FAT + S.

^‡P <0.05 vs. FAT, FRU.

^§P <0.05 vs. FRU.

^||P <0.05 vs. STC.