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Lung sections from rat tissue showing particle uptake at Days 2 (A and B), 30 (C and D), and 90 (E and F) post-nano-TiO2 exposure. Particle aggregates (arrows) can be found in alveolar macrophages at Days 2 and 30, and mainly in the interstitium at Day 90. The tissues were stained with hematoxylin-eosin. (See colour version of this figure online at http://www.informahealthcare.com/imt)
