Figure 4.
Protection from liver injury in HIF-1α(Hep-/-) mice after chronic ethanol challenge.
(A) Liver-weight to body-weight ratio in HIF-1α(Hep-/-) or control mice with chronic ethanol. (B) Triglycerides were quantified from whole livers of ethanol-fed or pair-fed HIF-1α(Hep-/-) or control mice. (C) Serum ALT data from HIF-1α(Hep-/-) and wild-type mice after chronic ethanol and LPS challenge. (D) Western blot showing HIF1α protein expression with chronic ethanol in control and HIF-1α(Hep-/-) mice, Densitometry in (E).