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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Prostate. 2010 Dec 1;70(16):1799–1808. doi: 10.1002/pros.21216

Figure 4. L1–10 decreased microvessel density in LuCaP 23.1 subcutaneous xeonografts and alters angiogenesis-associated gene expression.

Figure 4

(A) Microvessel density in control and L1–10 treated LuCaP 23.1 subcutaneous tumors * (p=0.012). Arrows indicate CD34 positive vessels in representative tumor samples. (B) Angiogenesis-associated gene expression (human epithelial and mouse stromal) in control and L1–10 treated LuCaP 23.1 subcutaneous tumors * (p≤0.05). mRNA expression was calculated relative to RPL13a mRNA expression and then normalized to angiopoietin-1 mRNA expression. For all experiments: control (n=9) and L1–10 treated (n=9). Results are plotted as mean ± SEM.