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. 2011 May 10;2(3):e00051-11. doi: 10.1128/mBio.00051-11

TABLE 2 .

Effect of putative inhibitors on SAM uptake by E. coli ATM915 expressing CTL843

Unlabeled SAM analoguesa Molecular structure Change (%)b
S-Adenosyl-l-methionine (SAM) graphic file with name mbo003111107t201.jpg −74 ± 8
S-Adenosyl-l-homocysteine (SAH) graphic file with name mbo003111107t202.jpg −84 ± 10
5′-Deoxy-5′-(methylthio)adenosine (MTA) graphic file with name mbo003111107t203.jpg 15 ± 5
Adenosylornithine (sinefungin) graphic file with name mbo003111107t204.jpg −10 ± 13
l-Adenosine graphic file with name mbo003111107t205.jpg 6 ± 8
l-Homocysteine graphic file with name mbo003111107t206.jpg 23 ± 5
l-Methionine graphic file with name mbo003111107t207.jpg 32 ± 9
a

One hundred micromolar of the unlabeled compound.

b

Change in radioactivity observed in presence of unlabeled compound compared to control with only 10 µM [14C] SAM.