TABLE 2 .
Unlabeled SAM analoguesa | Molecular structure | Change (%)b |
---|---|---|
S-Adenosyl-l-methionine (SAM) | −74 ± 8 | |
S-Adenosyl-l-homocysteine (SAH) | −84 ± 10 | |
5′-Deoxy-5′-(methylthio)adenosine (MTA) | 15 ± 5 | |
Adenosylornithine (sinefungin) | −10 ± 13 | |
l-Adenosine | 6 ± 8 | |
l-Homocysteine | 23 ± 5 | |
l-Methionine | 32 ± 9 |
One hundred micromolar of the unlabeled compound.
Change in radioactivity observed in presence of unlabeled compound compared to control with only 10 µM [14C] SAM.