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. 2011 May 23;121(6):2242–2253. doi: 10.1172/JCI44031

Figure 4. p40 prevents DSS-induced colitis in mice.

Figure 4

(A) Mice were treated with 3% DSS in drinking water for 4 or 7 days and were gavaged with pectin/zein control beads or beads containing p40 at 10 μg/mouse/d, beginning on the same day of DSS treatment until the end of the experiment. Control mice received water alone. sac, sacrifice. (B) Paraffin-embedded colon sections were stained with H&E for light microscopic assessment of epithelial damage. Original magnification, ×10. (C) Colon injury scores are shown. (D) The length of colon was measured. *P < 0.05 compared with water groups in WT or Egfrwa2 mice; #P < 0.05 compared with either WT mice treated with DSS or WT mice treated with DSS and control beads.