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. 2011 May 23;121(6):2242–2253. doi: 10.1172/JCI44031

Figure 5. p40 treats DSS-induced colitis in mice.

Figure 5

(A) Colitis was induced by 3% DSS treatment for 4 days, and then mice were administered p40 for the following 3 days before mice were sacrificed. Control mice received water alone. 3DR, 3-day recovery. (B) Paraffin-embedded colon sections were stained with H&E for light microscopic assessment of epithelial damage. Original magnification, ×10. (C) Colon injury scores are shown. (D) The length of colon was measured. *P < 0.05 compared with water groups in WT or Egfrwa2 mice; #P < 0.05 compared with WT mice treated either with DSS or with DSS and control beads. DSS-4D3DR, mice treated with DSS for 4 days and sacrificed 3 days after recovery with water; p40-3DR, mice administered p40 for the 3-day recovery period.