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. 2011 May 16;156(2):137–147. doi: 10.1159/000322597

Fig. 2.

Fig. 2

Inducible release of O2− by CD2-IL-5/rac2−/− eosinophils is diminished in comparison with wild-type eosinophils. a Time course of PMA-induced O2− release in splenocytes from CD2- IL-5 and CD2-IL-5/rac2−/− mice (500 ng/ml PMA; n = 9– 10). b PMA-induced O2− release from purified wild-type and CD2-IL-5/rac2−/− eosinophils. c Release of O2− from human and mouse eosinophils in response to PMA (500 ng/ml). d O2− generated from neutrophils from wild-type C57Bl/6 mice compared with rac2−/− mice. b–d n = 3–4. ∗∗ p < 0.01, ∗∗∗ p < 0.001.