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. 2011 May 31;8(5):e1000439. doi: 10.1371/journal.pmed.1000439

Figure 3. Systematic review and meta-analysis.

Figure 3

Systematic review and meta-analysis of studies investigating the relationship between haemoglobin concentration and prognosis in patients with stable coronary disease. Legend: aCI not reported in paper; standard error estimated from p-value. bReported by quintiles with fourth quintile as reference group; linear conversion by linear interpolation of relative risks across quintiles. cCardiovascular deaths and ACSs (all-cause mortality not reported in this study). dDerived from anaemia cutoff; HR 5.73 (95% CI 1.49–22.1) for anaemia (n = 14, mean haemoglobin  = 11.0) versus nonanaemia (n = 129, mean haemoglobin  = 14.4). eDerived from anaemia cutoff; HR 6.46 (95% CI 1.73–24.2) for anaemia (n = 71, mean haemoglobin  = 11.2) versus nonanaemia (n = 239, mean haemoglobin  = 14.0). fWe did not calculate risks from a linear model because it over-simplifies the shape of the relationship. gTotal number of patients is less than the sum of the individual cohort sizes because 861 patients were included in both angina and MI cohorts.