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. 2011 May 31;6(5):e17107. doi: 10.1371/journal.pone.0017107

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This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Canine brain had the greatest number of probesets without a gene symbol or gene name assigned. As proof-of-concept, these probesets within the top 50 canine brain selective list were re-mapped and underwent manual curation to link transcript information to expression data. Heatmap representing expression values for NetAffx™ unassigned canine probesets (NA) as well as LOC designated probesets in the top 50 brain selective expression list. Following manual curation the newly assigned gene symbols (curated gene symbol) are shown. Once these probesets were mapped to a known transcript, all other canine probesets for that transcript on the canine version 2.0 array were subsequently re-mapped and their relative expression is shown for comparison. In cases where the curated gene symbol is represented by (NA), this denotes that the probeset mapped unambiguously to an intronic region. Red represents increased and green decreased log-fold expression compared to the mean of all other tissues.