Table 2. Performance (per patient) of different microscopy methods using smear-positive case definition of one positive smear out of three collected specimens.
Direct ZN | Direct LED-FM | LED-FM after NaOCl | ||||
Pos | Neg | Pos | Neg | Pos | Neg | |
Positive culture | 67 | 26 | 68 | 25 | 73 | 20 |
Negative culture | 12 | 284 | 9 | 287 | 36 | 260 |
– Sensitivity, % [95%CI] | 72.0 [61.8–81.6] | 73.2 [62.9–81.8] | 78.5 [68.8–86.3] | |||
– Specificity, % [95%CI] | 95.9 [93.0–97.9] | 96.7 [94.3–98.6] | 87.8 [83.6–91.3] | |||
– Positive LR | 17.8 | 24.0 | 6.45 | |||
– Negative LR | 0.29 | 0.28 | 0.24 |
ZN: Ziehl Neelsen; LED-FM: light-emitting diode fluorescence microscopy; Pos: positive; Neg: negative.