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. 2011 May 31;6(5):e20175. doi: 10.1371/journal.pone.0020175

Table 2. Performance (per patient) of different microscopy methods using smear-positive case definition of one positive smear out of three collected specimens.

Direct ZN Direct LED-FM LED-FM after NaOCl
Pos Neg Pos Neg Pos Neg
Positive culture 67 26 68 25 73 20
Negative culture 12 284 9 287 36 260
– Sensitivity, % [95%CI] 72.0 [61.8–81.6] 73.2 [62.9–81.8] 78.5 [68.8–86.3]
– Specificity, % [95%CI] 95.9 [93.0–97.9] 96.7 [94.3–98.6] 87.8 [83.6–91.3]
– Positive LR 17.8 24.0 6.45
– Negative LR 0.29 0.28 0.24

ZN: Ziehl Neelsen; LED-FM: light-emitting diode fluorescence microscopy; Pos: positive; Neg: negative.