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. 2011 May 31;6(5):e20241. doi: 10.1371/journal.pone.0020241

Table 2. Listing of the registration parameters used in the nonlinear model-building process.

Step size (mm) Iterations Gaussian Blur (mm)
8 30 16
8 30 8
4 30 8
4 30 4
2 10 4
2 10 2

At each stage, the intensity-blurred images were matched to one another. A 3D simplex optimization was used with stiffness, weight, similarity parameters set to 1, 1, and 0.3 respectively (as optimized in [41]). In each case the spherical search area around each node was set to 3 x step size.