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. 2011 May 31;6(5):e20362. doi: 10.1371/journal.pone.0020362

Figure 3. miR-34 as a post-transcriptional repressor of E2F1.

Figure 3

(A) Effect of miR-34a on E2F1 protein levels in SHSY5Y cells. *p<0.05 vs Ctl/Lipo; φ p<0.05 vs miR-34a alone; n = 6 for each group. (B) Inability of miR-34 to affect the overexpression of h-eag1 mRNA induced by transfection of the plasmid expressing the E2F1 cDNA. *p<0.05 vs Ctl/Lipo; n = 4 for each group. (C) Repression of h = eag1 protein levels by miR-34a in the presence of E1F1 overexpression by the vector containing the E2F1 cDNA. *p<0.05 vs Ctl/Lipo; φ p<0.05 vs miR-34a alone; n = 4 for each group.