Figure 1. Phylogenetic relationships of the SID and Argonaute proteins from N. lugens and other species, and the structure of the N. lugens Aubergine protein.

Phylogenetic analysis of (A) SID protein sequences, and (B) Argonaute protein sequences from N. lugens and other animals were conducted using MEGA 4.0; nodes with a bootstrap similarity of at least 50% are shown. (C) Conserved domains of Aubergine in N. lugens. It has the PAZ and Piwi domains that are typical motifs of Argonaute family proteins. The catalytic triad DDH is also shown. Sequence motifs were predicted by the NCBI Conserved Domains Server.