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. 2011 May 31;6(5):e20572. doi: 10.1371/journal.pone.0020572

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Volman et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A Color panel is the surface plot of firing rate (averaged over non-overlapping bins of 100 ms and over all model neurons) vs. the probability to increase the leak conductance by in each one of the model neurons from the affected area (,) that did not previously share gap junction connection. Color code is blue for low firing rate and red for high firing rate. Horizontal axis is simulation time ([0–10] seconds). Background noise intensity for the set of model neurons was perturbed at (dashed red line through Panels B,C), and progressively increased to achieve 5-fold higher values at time 10 seconds (scale bar in lowest panel). Membrane leak conductance for model neurons was increased (as specified by ) at time (dashed blue line through Panels B,C). B Raster plot of network's activity for . Other parameters: . C Third panel: Raster plot of network's activity for . Other parameters: .

Inline graphic — A Color panel is the surface plot of firing rate (averaged over non-overlapping bins of 100 ms and over all model neurons) vs. the probability to increase the leak conductance by in each one of the model neurons from the affected area (,) that did not previously share gap junction connection. Color code is blue for low firing rate and red for high firing rate. Horizontal axis is simulation time ([0–10] seconds). Background noise intensity for the set of model neurons was perturbed at (dashed red line through Panels B,C), and progressively increased to achieve 5-fold higher values at time 10 seconds (scale bar in lowest panel). Membrane leak conductance for model neurons was increased (as specified by ) at time (dashed blue line through Panels B,C). B Raster plot of network's activity for . Other parameters: . C Third panel: Raster plot of network's activity for . Other parameters: .