Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Regulation of Pgc-1α and mitochondrial function by c-Myc, T-H and aging. Aging and T-H are known to reduce Pgc-1α activity. Our results indicate that c-Myc expression increases following T-H in both age groups and this transcription factor might be the mediator for decreased Pgc-1α following injury, resulting in diminished mitochondrial biogenesis and function.
