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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Neurogastroenterol Motil. 2011 Feb 9;23(4):379–e164. doi: 10.1111/j.1365-2982.2011.01675.x

Figure 2.

Figure 2

Jejunal circular smooth muscle spontaneous and bethanechol stimulated contractions recorded from sham and TBX17.5% groups of mice. The recorded spontaneous muscle activity quantified over a period of 10 minutes was significantly diminished after subcutaneous implantation of the TBX for 21 hours compared to sham treated mice (0.63±0.089 vs. 0.23±0.052 mg/mm2/sec, p<0.05). Similarly, bethanechol dose-response curve generated from the tissue injury mice was also markedly suppressed compared to sham (bethanechol 100μM: 3.48±0.392 vs. 1.96±0.564, p<0.05).