Table 3.
Pretreatment | Baseline DA Levels | Baseline 5-HT Levels |
---|---|---|
pg/20 μl | pg/20 μl | |
Saline | 4.9 ± 0.9aa, c | 8.8 ± 2.9 |
1 hr (−) TCP | 11.3 ± 2.7 | 8.3 ± 2.7 |
20 hr (±) TCP | 34.0 ± 8.8b | 16.5 ± 4.0 |
1 hr (+) TCP | 29.2 ± 5.0 | 25.2 ± 4.8d |
1 hr (±) TCP | 31.5 ± 4.9b | 20.4 ± 3.5 |
p<0.01 vs. 20-hr (±) TCP, 1 hr (±) TCP
p<0.05 vs. 1-hr (−)TCP,
p<0.05 vs. (+) TCP,
p≤0.05 vs. 1 hr (−) TCP. n = 4–11/group. Data for the individual pretreatments at t=60 min are pooled from animals later given either saline or nicotine, i.v. at t= 180 min.