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. Author manuscript; available in PMC: 2012 Jun 13.
Published in final edited form as: Brain Res. 2011 Apr 22;1395:94–107. doi: 10.1016/j.brainres.2011.04.036

Figure 7. Basal DA and DA metabolite levels in ST are not affected by expression of hSNCA and/or silencing vector 9 weeks after injection.

Figure 7

Rats were euthanized 9 weeks after injection and striatae were examined for DA and DA metabolite levels as a measure of SN DA neuron function. No effects on DA or DA metabolite levels in injected ST (closed bars) compared to uninjected ST (open bars) were observed, suggesting that hSNCA expression and silencing does not effect total basal levels of DA and DA turnover in the ST. Mean±SEM; comparison of injected and uninjected ST was analyzed using a Mann-Whitney t-test and comparison between treatments was analyzed using a Kruskal-Wallis one-way ANOVA, followed by Dunn’s post-hoc tests; asterisks denote significance as follows; *=p≤0.05, **=p≤0.01.