Table 1.
Parameters for analysis: | ||||
---|---|---|---|---|
AAV Treatment Group |
Morphology | Forelimb Use – 9 wk |
Nigrostriatal- projecting DA neurons – 9 wk |
DA/DA metabolites – 9 wk |
hSNCA | N/A | 16 | 9 | N/A |
hSNCA+hrGFP | 4wk-n=10 9wk-n=7 |
7 | n.d. | 5 |
hSNCA+shRNA-
Luc |
4wk-n=4 9wk-n=5 |
4 | n.d. | 3 |
hSNCA+shRNA-
SNCA |
4wk-n=3 9wk-n=8 |
28 | 10 | 6 |
shRNA-Luc | 9wk-n=4 | 5 | n.d. | 4 |
shRNA-SNCA | 9wk-n=9 | 21 | 6 | 6 |
n.d., not determined