Table 1.
Parameter ±SEM |
Sal-Sal | Sal-Coc | Coc-Sal | Coc-Coc |
---|---|---|---|---|
Sum in first 15 Minutes | 17.93 ±1.40 | 32.16 ±5.08 | 25.89 ±3.62 | 88.62 ±4.91* |
Average Number of Behaviors | 17.89 ±1.69 | 24.62 ±2.27 | 22.87 ±2.22 | 45.76 ±3.55* |
Sum of Behaviors | 304.1 ±28.76 | 418.5 ±38.54 | 388.67 ±37.70 | 777.78 ±60.38* |
Circulating Corticosterone (ng/ml) | 139.6 ±26.29 | 111.52 ±11.83 | 114.92 ±24.38 | 115.5 ±19.51 |
indicates that the value is significantly different from each of the other categories based on ANOVA followed by Fisher’s posthoc analysis at P< 0.05. Each group is designated by the two treatments, saline (Sal) or cocaine (Coc). The first listed is the daily injection delivered for 5 days prior to the day of testing. The second drug listed is the final challenge delivered 60 min prior to death.