Table 1.
Variable | Total |
Males |
Females |
|||||||||||||||
Cases (n = 222) |
Controls (n = 336) |
ORb | 95% CI | Cases (n = 69) |
Controls (n = 141) |
ORb | 95% CI | Cases (n = 153) |
Controls (n = 194) |
ORb | 95% CI | |||||||
No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |||||||
Child's age, years | ||||||||||||||||||
0 | 45 | 20.27 | 76 | 22.62 | 1.00 | Referent | 20 | 28.99 | 37 | 26.24 | 1.00 | Referent | 25 | 16.34 | 39 | 20.10 | 1.00 | Referent |
1–4 | 72 | 32.43 | 81 | 24.11 | 1.50 | 0.92, 2.44 | 32 | 46.38 | 34 | 24.11 | 1.74 | 0.84, 3.60 | 40 | 26.14 | 46 | 23.71 | 1.36 | 0.70, 2.62 |
5–10 | 39 | 17.57 | 84 | 25.00 | 0.78 | 0.46, 1.33 | 3 | 4.35 | 30 | 21.28 | 0.19 | 0.05, 0.68 | 36 | 23.53 | 54 | 27.84 | 1.04 | 0.54, 2.00 |
11–14 | 66 | 29.73 | 95 | 28.27 | 1.17 | 0.72, 1.90 | 14 | 20.29 | 40 | 28.37 | 0.65 | 0.29, 1.47 | 52 | 33.99 | 55 | 28.35 | 1.48 | 0.79, 2.77 |
Birth weight, g | ||||||||||||||||||
≤3,000 | 56 | 25.23 | 74 | 22.02 | 1.33 | 0.89, 2.01 | 13 | 18.84 | 24 | 17.02 | 1.41 | 0.65, 3.06 | 43 | 28.10 | 49 | 25.26 | 1.24 | 0.76, 2.02 |
3,001–4,000 | 130 | 58.56 | 229 | 68.15 | 1.00 | Referent | 38 | 55.07 | 99 | 70.21 | 1.00 | Referent | 92 | 60.13 | 130 | 67.01 | 1.00 | Referent |
≥4,001 | 36 | 16.22 | 33 | 9.82 | 1.92 | 1.14, 3.23 | 18 | 26.09 | 18 | 12.77 | 2.61 | 1.23, 5.53 | 18 | 11.76 | 15 | 7.73 | 1.70 | 0.81, 3.54 |
Maternal age at index pregnancy, years | ||||||||||||||||||
≤24 | 70 | 31.53 | 94 | 27.98 | 1.10 | 0.73, 1.68 | 20 | 28.99 | 30 | 21.28 | 1.90 | 0.89, 4.07 | 50 | 32.68 | 64 | 32.99 | 0.81 | 0.48, 1.35 |
25–29 | 81 | 36.49 | 120 | 35.71 | 1.00 | Referent | 20 | 28.99 | 57 | 40.43 | 1.00 | Referent | 61 | 39.87 | 63 | 32.47 | 1.00 | Referent |
30–34 | 46 | 20.72 | 90 | 26.79 | 0.76 | 0.48, 1.19 | 17 | 24.64 | 43 | 30.50 | 1.13 | 0.53, 2.41 | 29 | 18.95 | 46 | 23.71 | 0.65 | 0.36, 1.17 |
≥35 | 25 | 11.26 | 32 | 9.52 | 1.16 | 0.64, 2.10 | 12 | 17.39 | 11 | 7.80 | 3.11 | 1.19, 8.15 | 13 | 8.50 | 21 | 10.82 | 0.64 | 0.29, 1.39 |
Parity at index pregnancy | ||||||||||||||||||
1 | 61 | 27.48 | 109 | 32.44 | 1.00 | Referent | 16 | 23.19 | 50 | 35.46 | 1.00 | Referent | 45 | 29.41 | 59 | 30.41 | 1.00 | Referent |
2 | 71 | 31.98 | 92 | 27.38 | 1.38 | 0.89, 2.14 | 24 | 34.78 | 39 | 27.66 | 1.92 | 0.90, 4.11 | 47 | 30.72 | 52 | 26.80 | 1.19 | 0.68, 2.06 |
3 | 45 | 20.27 | 79 | 23.51 | 1.02 | 0.63, 1.65 | 19 | 27.54 | 27 | 19.15 | 2.20 | 0.98, 4.96 | 26 | 16.99 | 52 | 26.80 | 0.66 | 0.36, 1.21 |
4 or more | 45 | 20.27 | 56 | 16.67 | 1.44 | 0.87, 2.37 | 10 | 14.49 | 25 | 17.73 | 1.25 | 0.50, 3.15 | 35 | 22.88 | 31 | 15.98 | 1.48 | 0.80, 2.75 |
Maternal race | ||||||||||||||||||
White | 174 | 78.38 | 289 | 86.01 | 1.00 | Referent | 57 | 82.61 | 124 | 87.94 | 1.00 | Referent | 117 | 76.47 | 164 | 84.54 | 1.00 | Referent |
Nonwhite | 48 | 21.62 | 47 | 13.99 | 1.70 | 1.09, 2.64 | 12 | 17.39 | 17 | 12.06 | 1.54 | 0.69, 3.43 | 36 | 23.53 | 30 | 15.46 | 1.68 | 0.98, 2.89 |
Maternal education | ||||||||||||||||||
High school or less | 87 | 39.19 | 98 | 29.17 | 1.00 | Referent | 24 | 34.78 | 31 | 21.99 | 1.00 | Referent | 63 | 41.18 | 67 | 34.54 | 1.00 | Referent |
Some post-high school | 65 | 29.28 | 108 | 32.14 | 0.68 | 0.45, 1.03 | 21 | 30.43 | 48 | 34.04 | 0.57 | 0.27, 1.18 | 44 | 28.76 | 60 | 30.93 | 0.78 | 0.46, 1.31 |
College graduate | 50 | 22.52 | 97 | 28.87 | 0.58 | 0.37, 0.91 | 22 | 31.88 | 44 | 31.21 | 0.65 | 0.31, 1.35 | 28 | 18.30 | 52 | 26.80 | 0.57 | 0.32, 1.02 |
Advanced degree | 20 | 9.01 | 33 | 9.82 | 0.68 | 0.37, 1.28 | 2 | 2.90 | 18 | 12.77 | 0.14 | 0.03, 0.68 | 18 | 11.76 | 15 | 7.73 | 1.28 | 0.59, 2.75 |
Annual household income, $ | ||||||||||||||||||
<20,000 | 63 | 28.38 | 62 | 18.45 | 1.00 | Referent | 21 | 31.34 | 27 | 19.15 | 1.00 | Referent | 42 | 27.45 | 35 | 18.32 | 1.00 | Referent |
20,001–30,000 | 55 | 24.77 | 87 | 25.89 | 0.62 | 0.38, 1.01 | 14 | 20.90 | 34 | 24.11 | 0.53 | 0.23, 1.23 | 41 | 26.80 | 53 | 27.75 | 0.65 | 0.35, 1.18 |
30,001–50,000 | 53 | 23.87 | 102 | 30.36 | 0.51 | 0.32, 0.83 | 18 | 26.87 | 43 | 30.50 | 0.54 | 0.24, 1.19 | 35 | 22.88 | 58 | 30.37 | 0.50 | 0.27, 0.93 |
>50,000 | 49 | 22.07 | 82 | 24.40 | 0.59 | 0.36, 0.97 | 14 | 20.90 | 37 | 26.24 | 0.49 | 0.21, 1.13 | 35 | 22.88 | 45 | 23.56 | 0.65 | 0.35, 1.22 |
Vitamin use during pregnancy | ||||||||||||||||||
Yes | 190 | 85.59 | 309 | 92.24 | 1.00 | Referent | 62 | 89.86 | 134 | 95.04 | 1.00 | Referent | 128 | 83.66 | 174 | 90.16 | 1.00 | Referent |
No | 32 | 14.41 | 26 | 7.76 | 0.50 | 0.29, 0.86 | 7 | 10.14 | 7 | 4.96 | 0.46 | 0.16, 1.38 | 25 | 16.34 | 19 | 9.84 | 0.56 | 0.30, 1.06 |
Abbreviations: CI, confidence interval; OR, odds ratio.
Missing information on sex for 1 control.
Odds ratio from logistic regression.