Table 2.

Summary of Estimated Regression Coefficients From Final Mixed Models for Associations Between Baseline HSV-2 Seropositivity and 1) HIV Viral Load and 2) CD4 Count/100 Over Study Follow-up, HIV Epidemiology Research Study, United States, 1993–2000

Variable	HIV Log Viral Load Model			CD4 Count/100 Model
	$\widehat{\text{β}}$a	SE	P Value	$\widehat{\text{β}}$a	SE	P Value
Intercept	2.80	0.12	<0.0001	3.95	0.47	<0.0001
HSV-2	0.02	0.06	0.75	−0.18	0.17	0.28
Time since baseline	0.38	0.03	<0.0001	−0.68	0.05	<0.0001
HSV-2 × time since baseline	−0.02	0.02	0.23	0.08	0.03	0.006
Time since baseline squared	−0.10	0.01	<0.0001	0.09	0.01	<0.0001
Baseline CD4 count/100b	−0.34	0.05	<0.0001
Baseline viral load (log10)b				−1.91	0.39	<0.0001
Race	0.18	0.06	0.002	0.31	0.15	0.04
Presence of genital infections	0.12	0.05	0.03

Abbreviations: HIV, human immunodeficiency virus; HSV-2, herpes simplex virus type 2; SE, estimated standard error.

^aEstimated regression coefficients from the final mixed model.

^bVariable is centered at the median.