Table 3.
Antihypertensive Medication (ATC Codea) Prescriptions/Yearb by Gestational Agec | Unadjusted |
Adjusted Model 1d |
Adjusted Model 2e |
|||
OR | 95% CI | OR | 95% CI | OR | 95% CI | |
≥1 prescriptions/year | ||||||
23–27 weeks | 2.42 | 1.07, 5.46 | 2.49 | 1.10, 5.63 | 2.51 | 1.11, 5.68 |
28–32 weeks | 1.60 | 1.26, .2.02 | 1.57 | 1.24, 1.98 | 1.51 | 1.20, 1.91 |
33–34 weeks | 1.33 | 1.10, 1.61 | 1.28 | 1.06, 1.55 | 1.24 | 1.03, 1.51 |
35–36 weeks | 1.28 | 1.15, 1.42 | 1.26 | 1.13, 1.40 | 1.25 | 1.12, 1.39 |
37–42 weeks | 1.00 | 1.00 | 1.00 | |||
≥43 weeks | 1.12 | 1.00, 1.25 | 1.05 | 0.94, 1.18 | 0.97 | 0.86, 1.09 |
≥2 prescriptions/year | ||||||
23–27 weeks | 3.60 | 1.59, 8.13 | 3.71 | 1.64, 8.40 | 3.75 | 1.66, 8.49 |
28–32 weeks | 1.68 | 1.28, 2.21 | 1.65 | 1.25, 2.17 | 1.58 | 1.20, 2.09 |
33–34 weeks | 1.49 | 1.20, 1.86 | 1.43 | 1.15, 1.77 | 1.38 | 1.11, 1.72 |
35–36 weeks | 1.31 | 1.15, 1.49 | 1.28 | 1.13, 1.46 | 1.27 | 1.12, 1.45 |
37–42 weeks | 1.00 | 1.00 | 1.00 | |||
≥43 weeks | 1.19 | 1.04, 1.36 | 1.11 | 0.97, 1.28 | 1.02 | 0.89, 1.17 |
≥3 prescriptions/year | ||||||
23–27 weeks | 3.69 | 1.37, 9.95 | 3.78 | 1.40, 10.2 | 3.83 | 1.42, 10.4 |
28–32 weeks | 1.75 | 1.25, 2.45 | 1.71 | 1.22, 2.39 | 1.65 | 1.18, 2.30 |
33–34 weeks | 1.79 | 1.39, 2.29 | 1.70 | 1.32, 2.18 | 1.65 | 1.29, 2.12 |
35–36 weeks | 1.31 | 1.12, 1.54 | 1.28 | 1.09, 1.50 | 1.27 | 1.08, 1.49 |
37–42 weeks | 1.00 | 1.00 | 1.00 | |||
≥43 weeks | 1.20 | 1.01, 1.42 | 1.11 | 0.94, 1.32 | 1.02 | 0.86, 1.21 |
≥4 prescriptions/year | ||||||
23–27 weeks | 4.52 | 1.44, 14.2 | 4.62 | 1.47, 14.5 | 4.68 | 1.49, 14.7 |
28–32 weeks | 1.97 | 1.31, 2.94 | 1.90 | 1.27, 2.85 | 1.80 | 1.20, 2.70 |
33–34 weeks | 1.82 | 1.33, 2.50 | 1.72 | 1.26, 2.35 | 1.65 | 1.20, 2.26 |
35–36 weeks | 1.28 | 1.04, 1.57 | 1.25 | 1.01, 1.53 | 1.23 | 1.00, 1.51 |
37–42 weeks | 1.00 | 1.00 | 1.00 | |||
≥43 weeks | 1.20 | 0.97, 1.49 | 1.11 | 0.90, 1.38 | 0.99 | 0.80, 1.23 |
Abbreviations: ATC, Anatomical Therapeutic Chemical (Classification); CI, confidence interval; OR, odds ratio.
Code(s) C02, C03, C07, C08, and/or C09.
Outcome variable.
Predictor variable.
Adjusted for infant's date of birth, infant's gender, maternal marital status, maternal education, family income, and maternal prescription of antihypertensive medications (≥1 prescriptions/year) during the follow-up period (July 1, 2005, through December 31, 2009).
Adjusted for the same variables included in adjusted model 1, as well as fetal growth.