Table 3.

Post-Hoc GEE model including vascular risk factors significantly associated with cognition in individual models

	Beta (95% CI)	p-value
intercept	−1.251 (−3.05, 0.55)	0.17
time (diagnosis on)	0.302 (−0.031, 0.640)	0.08
Female	0.073 (−0.168, 0.313)	0.55
African-American	−0.219 (−0.665, 0.226)	0.34
Hispanic	−0.292 (−0.733, 0.150)	0.20
Education (per additional year)	0.038 (0.019, 0.057)	<0.001
Age at diagnosis (per additional year)	−0.010 (−0.023, 0.002)	0.11
cohort (1999 vs 1992)	0.008 (−0.099, 0.114)	0.89
Time between lipid draw and AD incidence	0.003 (−0.050, 0.057)	0.90
diabetes history	−0.082 (−0.296, 0.133)	0.45
time * diabetes history	−0.046 (−0.106, 0.014)	0.14
LDL-C	0.000 (−0.003, 0.002)	0.67
time * LDL-C	−0.001 (−0.002, 0.000)	0.001
HDL-C (log-transformed)	0.252 (−0.059, 0.562)	0.11
time * Log HDL-C	−0.060 (−0.144, 0.023)	0.16

Significant factors associated with differential change in cognition over time are bolded. Time was expressed in years.