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. 2011 Feb 8;2:181. doi: 10.1038/ncomms1182

Figure 3. Correction of anaemia in Uba5-deficient mice by expression of Uba5 in erythroid lineage.

Figure 3

(a) Embryonic morphology of Uba5 rescue mice. Representative photographs of Uba5+/+;TgUba5 and Uba5−/−;TgUba5 embryos at various embryonic stages. Scale bar, 2 mm. (b) Haematoxylin and eosin-stained fetal liver sections of Uba5+/+;TgUba5 and Uba5−/−;TgUba5 mice at E11.5. Scale bars: left panel, 1 mm; right panel, 20 μm. (c) Number of erythroid cells in fetal livers of Uba5+/+;TgUba5 and Uba5−/−;TgUba5 mice at E11.5. Data are means±s.d. of five mice from each group. (d) Wright–Giemsa-stained samples of peripheral blood cytospin cells prepared from control and rescued mice at E11.5. Scale bar, 20 μm. (e) Percentage of abnormal erythrocytes shown in d. Data are means±s.d. of five mice in each group.