Table 1.

Classification of ataxias

1 Hereditary ataxias 1.1 Autosomal recessive ataxias 1.1.1 Friedreich ataxia (FRDA) 1.1.2 Ataxia telangiectasia (AT) 1.1.3 Autosomal recessive ataxia with oculomotor apraxia type 1 (AOA1) 1.1.4 Autosomal recessive ataxia with oculomotor apraxia type 2 (AOA2) 1.1.5 Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) 1.1.6 Ataxia with isolated vitamin E deficiency (AVED) 1.1.7 Marinesco-Sjögren syndrome (MSS) 1.1.8 Autosomal recessive ataxias due to POLG mutations (MIRAS, SANDO) 1.1.9 Cerebrotendinous xanthomatosis (CTX) 1.1.10 Refsum disease 1.1.11 Abetalipoproteinemia 1.1.12 Other autosomal recessive ataxias 1.2 Autosomal dominant ataxias 1.2.1 Spinocerebellar ataxias (SCA) 1.2.2 Episodic ataxias (EA) 1.3 X-linked ataxias 1.3.1 Fragile X–associated tremor/ataxia syndrome (FXTAS) 1.3.2 Other X-linked ataxias 1.4 Ataxias due to mitochondrial mutations 2 Non-hereditary degenerative ataxias 2.1 Multiple system atrophy, cerebellar type (MSA-C) 2.2 Sporadic adult-onset ataxia of unknown origin (SAOA) 3 Acquired ataxias 3.1 Alcoholic cerebellar degeneration (ACD) 3.2 Ataxia due to other toxic reasons 3.3 Ataxia due to acquired vitamin deficiency 3.4 Paraneoplastic cerebellar degeneration 3.5 Other immune-mediated ataxias 3.6 Ataxia in chronic CNS infection 3.7 Superficial siderosis