Table 1.
Specific PDGF AA inducible or repressible microRNAs
| miR | Chromosome | Fold-changes | P-value | Expression in cancer | Function |
|---|---|---|---|---|---|
| mir-126-5p | 9q24 | −19.1 | 4.54E–05 | Lost in breast cancer | Suppresses cell proliferation |
| miR-149 | 2q37 | 4.8 | 0.0003 | Down in glioblastoma, melanoma | Not known |
| miR-185 | 22q11.21 | 3.9 | 0.0089 | Up in hepatocellular and bladder cancer | Not known |
| miR-663 | 20p11.21 | 5.5 | 0.0011 | Up in ovarian, lost in breast cancer | Epigenetic silencing in breast cancer |
| miR-769-5p | 19q13.33 | 5.2 | 0.0087 | Not known | Not known |
| Let-7d | 9q22 | −9.5 | 0.0048 | Down in hepatocellular, ovarian, lung cancer | Suppresses cell proliferation |
| miR-770P | 14q42 | −6.0 | 0.002 | Not known | Not known |