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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: J Ultrasound Med. 2011 Mar;30(3):333–345. doi: 10.7863/jum.2011.30.3.333

Table 2.

Kinetics of contrast agent relative to stages of ovarian cancer in hens.

Ovarian
pathology		 Time of
arrival of
contrast
agent
(secs)		 Time to
reach peak
intensity
(secs)		 Time of
wash-out
(secs)		 Percentage of
hens with
OVCA
detected by
Time-of-
Washout* 		Area under
the curve
(AUC)		 Number of
hens with
OVCA
detected by
AUC*
Normal 15 ± 0.82 (14–16)   21 ± 0.81 (20–22) 51 ± 2.44 (48–56) Ref 5496.94 ± 1439.80 Ref
Microscopic OVCA 14± 1.21 (12–15) 20 ± 2.04 (17–22) 72 ± 4.24 (69–81) 100% (P<0.01) 15310.86 ± 2771.64 86% (P<0.05)
Early stage OVCA 14 ± 0.96 (13–15) 19 ± 1.29 (17–20) 120 ± 11.15 (108–135) 100% (P<0.01) 49404.00 ± 10957.71 100% (P<0.05)
Late stage OVCA 13 ± 1.12 (11–14) 18 ± 0.94 (17–19) 150 ± 4.94 (142–156) 100% (P<0.01) 80607.00± 15247.76 100% (P<0.05)

Ref = reference

*

above the cut-off value (mean of normal ± 3SD) for Time-of-Washout and AUC.