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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Cancer Res. 2008 Dec 1;68(23):9996–10003. doi: 10.1158/0008-5472.CAN-08-2492

Figure 3.

Figure 3

Increased chimeric tumor growth in mouse s.c. space by coinjection of Pt1-C or Pt1-N with C4-2-Luc cells. A, representative chimeric tumor growth in athymic mice after coinjecting Pt1-C or Pt1-N cells and C4-2-Luc cells s.c. Larger chimeric tumors were detected with Pt1-C/C4-2 than Pt1-N/C4-2. Tumor size distributions were obtained at the end of the study. Pt1-C was more inductive than Pt1-N for the growth of androgen-independent and bone metastatic C4-2 cells (P = 0.001), confirmed by mouse serum PSA (P = 0.002; B) and tumor-associated luciferase activity (P = 0.021; C).