Table 1. Gene expression of the RNAi apparatus is unaltered by spaceflight.
| RNAi component protein | Gene name | Description | Ground control mRNA expression (av. fold change) | Spaceflight mRNA expression (av. fold change) | Significance |
| Dicer (RNase III) | rnh-1.0 | Predicted RNase H | 1.01±0.11 | 1.00±0.10 | P>0.05 |
| rnh-1.1 | RNase H family member | 0.47±0.02 | 0.49±0.06 | P>0.05 | |
| rnh-1.2 | RNase H family member | 1.29±0.11 | 1.09±0.33 | P>0.05 | |
| rnh-1.3 | RNase H family member | 1.03±0.01 | 1.07±0.09 | P>0.05 | |
| rnh-2 | RNase H2 subunit | 0.96±0.11 | 1.07±0.10 | P>0.05 | |
| dcr-1 | Dicer family member | 0.99±0.04 | 1.18±0.10 | P>0.05 | |
| drh-1 | DExH-box helicase | 1.02±0.10 | 1.12±0.11 | P>0.05 | |
| drh-3 | Dicer related helicase family member | 0.98±0.07 | 1.12±0.09 | P>0.05 | |
| PIWI | ppw-1 | PIWI-domain containing family member | 1.11±0.05 | 1.00±0.06 | P>0.05 |
| ppw-2 | PIWI-domain containing family member | 1.01±0.19 | 0.94±0.11 | P>0.05 | |
| prg-1 | PIWI protein | 1.07±0.07 | 1.03±0.05 | P>0.05 | |
| rde-1 | PIWI family member | 1.07±0.06 | 1.08±0.09 | P>0.05 | |
| Argonaute | ergo-1 | Endogenous argonaute family member | 1.05±0.07 | 1.20±0.04 | P>0.05 |
| sago-1 | Argonaute mutant family member | 1.03±0.09 | 0.89±0.05 | P>0.05 | |
| sago-2 | Argonaute homolog | 1.13±0.13 | 0.89±0.12 | P>0.05 | |
| RDE-4 | rde-4 | dsRNA binding protein | 1.07±0.10 | 1.19±0.09 | P>0.05 |
Adult hermaphrodites (2nd generation) collected at 8 d during spaceflight showed no change in gene expression for components of the RNAi machinery, which were not different ground controls (P>0.05). mRNA expression values are the average of 18 separate probes over six microarrays, and are relative to an internal control (1G controls).