Table 2.
IL-10 mRNA reactivity in tumor cells, macrophages and lymphocytes correlated with stage of melanoma evolution (melanoma in situ and invasive melanoma). R =0.68 (dependent variable: Clark level, P =0.0016). Adjusted R 2 =0.40. Melanoma in situ was ranked lowest in consideration of Breslow thickness.
| Clark level | melanoma cells | macrophages | lymphocytes | |
|---|---|---|---|---|
| Breslow thickness | 1 | 0.41* | −0.07 | 0.27 |
|
| ||||
| Clark level | 1 | 0.53** | −0.10 | 0.26 |
| melanoma cells | 0.62** | 1 | 0.37 | 0.23 |
| macrophages | −0.49* | 0.51* | 1 | 0.46* |
| lymphocytes | 0.38 | −0.19 | 0.52** | 1 |
Bold: significant correlations (*: P <0.05, **: P <0.01)
Above the main diagonal: Spearman’s correlation coefficients and P -values
Below the main diagonal: partial correlation coefficients and P -values