Table 4.
Meta-analysis of genetic associations in the European-derived sample set combined with WTCCC controls and the African- American sample set for markers in the IL21 gene.
Associated Allele |
European-derived with WTCCC Controls |
African-American | Meta-analysis | |||||
---|---|---|---|---|---|---|---|---|
SNP | OR (95% CI) | P Value | OR (95% CI) | P Value | OR (95% CI) | P Value | Pheterogeneity | |
rs6835457 | A | 1.10 (1.03–1.17) | 2.3×10−3 | 1.14 (1.03 1.26) | 0.012 | 1.11 (1.05–1.17) | 9.35×10−5 | 0.55 |
rs907715 | G | 1.16 (1.04–1.27) | 8.41×10−7 | 1.15 (1.04 1.27) | 0.0076 | 1.16 (1.10–1.22) | 2.17 ×10−8 | 0.83 |