Table 2.

Analysis of rare INDEL variants in RefSeq genes

For each class of INDELs examined, the number of rare INDELs (MAF <5%) versus the total number of INDELs in the class is listed. Two-tailed Fisher's exact tests were performed between the overall set of 10,003 INDELs that were genotyped on the array and each of the other classes that are listed. The data indicate that rare INDELs are over-represented in coding exons compared to the 10,003 INDELs. None of the remaining classes had such enrichment, suggesting that coding exons are the most sensitive to INDELs.