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Gene disruptions. The locations of three novel insertions within the coding exons of PRAMEF4 (chr1:12,864,273–12,864,302), CHI3L2 (chr1:111,573,857–111,573,923), and PARP4 (chr13:23,907,208–23,807,370) are shown. Unfilled black rectangles represent the exons (and parts of exons) in the untranslated region (UTR), where filled rectangles show protein-coding exons. (A,C) The two predicted Alu insertions mapped within a coding region; (B) an example of one Alu insertion in the UTR.
