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. Author manuscript; available in PMC: 2011 Jun 2.
Published in final edited form as: Infect Disord Drug Targets. 2007 Jun;7(2):140–158. doi: 10.2174/187152607781001772

Table 1.

Sulfotransferase Inhibitors

No. Ref. Structure Activity[a] (IC50) Type of Inhibition
1 [105] graphic file with name nihms295219t1.jpg >80% inhibition at 200 μM No data
2 [106] graphic file with name nihms295219t2.jpg 10 nM Competitive with PAP
3 [108] graphic file with name nihms295219t3.jpg 0.15 – 0.25 nM Non-competitive
4 [109] graphic file with name nihms295219t4.jpg 0.1 μM Competitive
5 [113] graphic file with name nihms295219t5.jpg 70 μM Non-competitive
6 [114] graphic file with name nihms295219t6.jpg 20 μM Competitive
7 [117] graphic file with name nihms295219t7.jpg 96 nM (Ki) Competitive
8 [99] graphic file with name nihms295219t8.jpg 50 μM No data
9 [99] graphic file with name nihms295219t9.jpg 30 μM No data
10 [119] graphic file with name nihms295219t10.jpg 30 μM Specific, reversible
11 [119] graphic file with name nihms295219t11.jpg 40 μM Specific, irreversible
[a]

Enzymes assayed: 1-4: EST; 5 : P-Selectin ; 6: GST; 7: β-AST-IV; 8: NodH; 9: GST-3; 10-11: TPST-2.