Fig. 2.

Effects of DC or ChA on CT-26 cell-induced COX-2 and matrix metalloproteinase (MMP) abundance and ERKs and c-jun N-terminal kinases (JNKs) phosphorylation. (A) DC or ChA inhibited CT-26 cell-induced COX-2 expression in Balb/cmice as determined by western blotting. (B) DC or ChA suppressed CT-26 cell-induced MMP-2 and -9 abundance in Balb/c mice as determined by gelatin zymography. (C) DC or ChA inhibited CT-26 cell-induced ERKs and JNKs phosphorylation in Balb/c mouse lung tissue homogenates. Data are representative of three independent experiments.