Fig. 4.
Broken arms fuse to the end of chromosomes. Example of a molecular cytogenetic analysis of a neuroectodermal tumor (92). The skygram was retrieved from the NCBI SKY/CGH database (93). The main structural alterations observed correspond to centromeric breaks (chromosomes 13 and 21) followed by fusion to telomeres (chromosomes 8, 15 and 20). Arrows indicate tandem orientation of the fusions. The fusion of chromosome 21 to chromosomes 8 and 15 classifies as a jumping translocation.