Figure 1.

Phylogenetic relationships of DQB1 alleles (left) and DQCAR alleles (right) based on their sequence data. Phylogenies of 14 DQB1 and 15 DQCAR alleles were reconstructed as detailed in Methods. (a) Number of chromosomes typed for DQB1 and DQCAR in a mixed population. (b) Number of DQCAR alleles associated with each DQB1 allele in the mixed population. (c) Number of uninterrupted CA repeats for each DQCAR allele observed in the mixed population, deduced from the sequenced alleles on Table 1. (d) The DQCAR alleles represented in the tree are the sequenced from Table 1. Areas with high DQCAR size variation (more than two DQCAR alleles found in association with a lineage) are boxed.