Table 3.

Mutated Sequences in Sample DNA

No.	Mutation	Positiona	No.	Mutation	Positiona
	gyrA			hFIX exon 7
1	T → G	250	1	T → C	30046
2	C → T	251	2	G → A	30070
3	G → C	253	3	T → G	30117
4	G → A	262	4	T → C	30134
5	G → C	262	5	AC deletion	30141
6	A → C	263
7	A → G	263
8	A → T	263		hFIX exon 8
9	TC → AT	250
10	TC → AA	250	1	C → T	30875
11	TC → AG	250	2	C → A	30973
12	TC → CT	250	3	C → A	31096
13	CA → TG	251	4	G → A	31119
14	CA → TT	251	5	G → T	31211
15	CA → AT	251	6b	A → G	30972
16	CA → TC	251		C → T	31328
17	CA → AC	251
18	GA → AT	262
19	GA → TT	262
20	AA → TT	263
21	TTC → CTT	249
22	TCA → GGT	250
23	GAA → ACT	262

^aNucleotide number starting from the first nucleotide of the coding sequence of gyrA (Munakata et al. 1994) or proposed transcription initiation site of hFIX (Yoshitake et al. 1985). 

^bThis sample carried a double mutation, at positions 30972 and 31328.