Table 2.
Meta analysis of the association of ACE I/D gene polymorphism with MCNS risk.
| Genetic contrasts | Group and subgroups | Studies number | Q test P value | Model | OR (95% CI) | P |
|---|---|---|---|---|---|---|
| D versus I | Overall | 6 | .64 | Fixed | 1.39 (1.09,1.76) | .007 |
| Asian | 4 | .46 | Fixed | 1.38 (1.07,1.79) | .01 | |
| Caucasian | 1 | — | Fixed | 1.69 (0.81,3.51) | .16 | |
| Africa | 1 | — | Fixed | 0.85 (0.23,3.13) | .81 | |
| DD versus (DI + II) | Overall | 6 | .45 | Fixed | 1.46 (1.01,2.11) | .04 |
| Asian | 4 | .36 | Fixed | 1.60 (1.07,2.38) | .02 | |
| Caucasian | 1 | — | Fixed | 1.01 (0.34,3.00) | .98 | |
| Africa | 1 | — | Fixed | 0.35 (0.02,6.86) | .49 | |
| II versus (DI + DD) | Overall | 6 | .58 | Fixed | 0.65 (0.44,0.96) | .03 |
| Asian | 4 | .70 | Fixed | 0.73 (0.49,1.09) | .12 | |
| Caucasian | 1 | — | Fixed | 0.08 (0.00,1.43) | .09 | |
| Africa | 1 | — | Fixed | 0.62 (0.03,12.62) | .76 | |