Table 1.

Advantages and Disadvantages of RRSO versus Surveillance

	Advantages	Disadvantages
RRSO	Most effective form of ovarian cancer risk reduction	Risks associated with the surgical procedure
	Associated with reduction in breast cancer risk, if performed prior to menopause	Adverse effects of hormonal deprivation (sudden onset of menopausal symptoms, increased risk of osteoporosis, increased risk of metabolic syndrome)
		Residual breast, ovarian and peritoneal cancer risk
		Concern about adverse effects on sexuality
		Concern that HRT may increase breast cancer risk, and thus reverse the beneficial effects of the surgery on breast cancer risk
Surveillance	Noninvasive	Multiple false positives
	May reduce cancer mortality	Majority of detected cases are diagnosed at late stage
		Does not reduce risk of ovarian cancer
		Adherence issues