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Alignment of the proteins predicted by the mouse and human GLC1A genes. (•) Amino acids conserved between mouse and human. The locations of disease-causing mutations identified previously in the human GLC1A gene are indicated (Stone et al. 1997; Alward et al. 1998). For each missense mutation, the mutant residue is shown directly above the wild-type amino acid. (1) The location of a nonsense mutation; (2) the location of an insertion mutation.
