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. 2011 May 20;13(6):680–689. doi: 10.1093/neuonc/nor045

Table 6.

Comparison of clinical characteristics of thalamic high-grade gliomas (HGGs) with supratentorial HGGs or pontine gliomas in pediatric patients

Distribution
Event-free survival
Overall survival
Thalamic vs pontine Thalamic vs supratentorial Thalamic vs pontine Thalamic vs supratentorial Thalamic vs. pontine Thalamic vs supratentorial
Total population NA NA NS <.0001 .0079 <.0001
Extent of surgery NA
 Total <.001a NA NA NA NA
 Subtotal NSa NS NS NS NS
 Partial NSa NS .0131 NS .0499
 Biopsy/no surgery <.001a NS .0357 NS NS
Grading NSa <.001a
 WHO III NS <.0001 .0133 <.0001
 WHO IV NS .0031 NS .0035
Sex NSa NSa
 Male NS <.0001 NS .0003
 Female NS .0002 .0141 .0028
Age at diagnosis
 Mean <.001b NSb NA NA NA NA
 <11 years NSa NSa NS .0001 NS .0016
 ≥11 years NS .0045 NS .006
Secondary HGG .014a NSa NA NA NA NA
Tumor syndrome NSa NSa NA NA NA NA
Primary metastasis .015a NSa NA NA NA NA
Cox regression analysis NA NA
 Tumor site NS <.001 NS <.001
 Tumor resection .016 <.001 .007 <.001
 Grading NS <.001 NS <.001
 Sex NS NS NS .035
 Age NS NS NS NS

NA indicates not applicable; NS indicates not significant; pontine indicates pediatric pontine gliomas; supratentorial indicates pediatric supratentorial HGGs; thalamic indicates pediatric HGG.

Statistical significance was determined by the two-sided chi-square test (a) or by Student's t-test (b). All other testing for statistical significance was performed by using the log rank test.