. 2011 May 20;13(6):680–689. doi: 10.1093/neuonc/nor045

Table 6.

Comparison of clinical characteristics of thalamic high-grade gliomas (HGGs) with supratentorial HGGs or pontine gliomas in pediatric patients

	Distribution		Event-free survival		Overall survival
	Thalamic vs pontine	Thalamic vs supratentorial	Thalamic vs pontine	Thalamic vs supratentorial	Thalamic vs. pontine	Thalamic vs supratentorial
Total population	NA	NA	NS	<.0001	.0079	<.0001
Extent of surgery	NA
Total		<.001^a	NA	NA	NA	NA
Subtotal		NS^a	NS	NS	NS	NS
Partial		NS^a	NS	.0131	NS	.0499
Biopsy/no surgery		<.001^a	NS	.0357	NS	NS
Grading	NS^a	<.001^a
WHO III			NS	<.0001	.0133	<.0001
WHO IV			NS	.0031	NS	.0035
Sex	NS^a	NS^a
Male			NS	<.0001	NS	.0003
Female			NS	.0002	.0141	.0028
Age at diagnosis
Mean	<.001^b	NS^b	NA	NA	NA	NA
<11 years	NS^a	NS^a	NS	.0001	NS	.0016
≥11 years			NS	.0045	NS	.006
Secondary HGG	.014^a	NS^a	NA	NA	NA	NA
Tumor syndrome	NS^a	NS^a	NA	NA	NA	NA
Primary metastasis	.015^a	NS^a	NA	NA	NA	NA
Cox regression analysis	NA	NA
Tumor site			NS	<.001	NS	<.001
Tumor resection			.016	<.001	.007	<.001
Grading			NS	<.001	NS	<.001
Sex			NS	NS	NS	.035
Age			NS	NS	NS	NS

NA indicates not applicable; NS indicates not significant; pontine indicates pediatric pontine gliomas; supratentorial indicates pediatric supratentorial HGGs; thalamic indicates pediatric HGG.

Statistical significance was determined by the two-sided chi-square test (a) or by Student's t-test (b). All other testing for statistical significance was performed by using the log rank test.