Table 1. Gene ontology analysis for the transactive genes associated with PADI4 binding in MCF-7 cells.

Gene ontology term	Aspect	P-value
membrane-enclosed lumen	CC	1.66E-12
intracellular organelle lumen	CC	3.43E-11
organelle lumen	CC	5.00E-11
nuclear lumen	CC	1.69E-09
ribonucleoprotein complex	CC	7.50E-09
non-membrane-bounded organelle	CC	1.35E-07
intracellular non-membrane-bounded organelle	CC	1.35E-07
macromolecule catabolic process	BP	3.11E-11
cellular macromolecule catabolic process	BP	4.88E-11
modification-dependent macromolecule catabolic process	BP	1.19E-09
modification-dependent protein catabolic process	BP	1.19E-09
proteolysis involved in cellular protein catabolic process	BP	1.57E-09
protein catabolic process	BP	1.62E-09
cellular protein catabolic process	BP	1.83E-09
nucleotide binding	MF	1.37E-07
ATPase activity	MF	6.05E-06
purine nucleotide binding	MF	2.22E-05
ribonucleotide binding	MF	2.62E-05
purine ribonucleotide binding	MF	2.62E-05
RNA binding	MF	3.89E-05
nucleoside binding	MF	1.14E-04

The analysis was performed for all three gene ontology aspects: cellular component (CC), biological process (BP) and molecular function (MF). The seven most significant gene ontology terms for each aspect are listed. For a more complete list of significantly enriched ontologies, refer to Table S2.