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. 2011 Jun 2;7(6):e1002071. doi: 10.1371/journal.ppat.1002071

Figure 3. IVIG alters the phenotype of macrophages and microglia.

Figure 3

CD45high infiltrates in brain and BS of control or IVIG treated 129 mice at d8 pi analyzed for (A) Gr-1+ cells; (B) Ly6Chigh and (C) FcεR1+ F480+ macrophages. (D) MHC II expression on CD45high macrophages and CD45int microglia isolated from BS or brains; frequencies and mean fluorescence intensity (MFI) of MHC II+ CD45 microglia (boxed regions) shown. (E) MHC I expression by CD45int microglia. Data representative of 2–3 experiments (n = 6–12 mice).